Automation Integration | icon96™ NGS Thermocycler | n6

icon96™ is Built
for Automation

Fully compatible with any liquid handling robot.
icon96 integrates into your automated NGS library prep pipeline via a comprehensive RESTful API — no workarounds, no compromises.

icon96 instrument
Universal Compatibility

Works With Your Existing
Automation Setup

icon96 is designed from the ground up to integrate into automated workflows. Whether you're running a Beckman, Hamilton, Tecan, Opentrons, or custom liquid handling platform, icon96 connects as a standard instrument node — no proprietary adapters, no modifications.

Read the Automation Brochure
Universal liquid handling robot compatibility (Beckman, Hamilton, Tecan, Opentrons, and others)
Standard fully skirted 96-well plate format — fits existing automation decks as-is
RESTful API with JSON Web Token authentication
Operates within private networks — no cloud dependency
Real-time device status monitoring via API endpoints
Secure, rate-limited endpoints for reliable LIMS/workflow integration
Workflow

A Fully Automated Run, Step by Step

01

System Verification

API polls instrument for idle status before initiating

02

Open Drawer

Robot sends open-drawer command; API confirms drawer state

03

Plate Load

Robotic arm places 96-well plate into the instrument

04

Close Drawer

API closes drawer; device state confirmed

05

Run Protocol

Experiment starts via API; AutoNorm monitors each well in real time

06

Plate Recovery

On completion, drawer opens; robotic arm retrieves plate

07

Data Retrieval

Fluorescence data and CSV reports pulled via API endpoint

All instrument commands are asynchronous. Status is polled via dedicated API endpoints to confirm completion before each next action.

Developer API

A Complete API for Autonomous Operation

The n6 Software API gives your automation platform full control over the icon96 instrument — from authentication to real-time experiment monitoring to data retrieval.

🔐

Authentication

JWT-based token authentication with short-lived access tokens and 50-day refresh tokens. Secure, standards-based.

⚙️

Device Control

Open/close drawer, monitor device state, reboot or shutdown — full hardware lifecycle management via REST calls.

📋

Protocol Management

List, upload, and execute validated protocols. Protocols are retrieved by name and assigned per experiment run.

📊

Experiment Monitoring

Start, stop, and track experiments in real time. Poll fluorescence data per well, or download CSV reports on completion.

Proof of Concept

The Fast and the Fluorescent: icon96™ Automation Integration in Action

We connected icon96 directly to a liquid handler and ran a complete automated NGS library prep workflow — from plate loading to real-time fluorescence monitoring to data retrieval. Every 96-well plate received individualized AutoNorm cycling, hands-free. See exactly how it was done.

Get Started

Ready to Automate? Here's How It Starts.

Automating with icon96 doesn't require custom hardware — it requires a plan. Here's the path most labs follow:

Get an icon96

The instrument is the foundation. Everything else connects to it.

Set Up Your Liquid Handler

Work with your liquid handling provider (Beckman, Hamilton, Tecan, Opentrons, etc.) to configure your deck and establish your automation script based on n6's API documentation.

Connect and Run

Using the n6 Software API, your system gains full control of icon96: plate loading, run initiation, real-time monitoring, and data retrieval — all automated.

n6 provides the API documentation and technical support. Your automation scripting is set up in collaboration with your liquid handler provider.